‘Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity’ – Lawrence B. Afrin, M.D. (2016) Dr. Afrin earned a B.S. in computer science from Clemson University in 1984 and then an M.D. at the Medical University of South Carolina (MUSC) in 1988, where he also pursued internal …
Mastocytosis is a type of mast cell disease in which the body produces too many mast cells. Mastocytosis also features inappropriate mast cell activation, in which mast cells too easily release their contents, called mediators. These mediators can cause a variety of unpredictable symptoms in both children and adults, including skin rashes, flushing, abdominal pain, …
Mast cells are sentinels or “guards” able to sense a wide range of threats upon the body (such as infections or environmental toxins). When a mast cell senses a threat, it “activates,” producing and releasing chemical signals (“mediators”) appropriate for assisting the body in managing the threat. In mast cell activation diseases (such as Mastocytosis …
***Most Recent Information for Patients Concerning Dr. Afrin’s Transition posted September 2017*** ***Dr. Afrin’s Commentary on Recent Affairs posted on Wednesday, July 26th, 2017*** ***Link to message on Dr. Lawrence Afrin’s transition posted on Thursday, July 20th, 2017*** A message from Dr. Lawrence Afrin: Tuesday, July 11, 2017 “Next month, I will be relocating to …
