What is Mastocytosis?

Mastocytosis is a type of mast cell disease in which the body produces too many mast cells. Mastocytosis also features inappropriate mast cell activation, in which mast cells too easily release their contents, called mediators. These mediators can cause a variety of unpredictable symptoms in both children and adults, including skin rashes, flushing, abdominal pain, …

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What is Mast Cell Activation Syndrome (MCAS)?

Mast cells are sentinels or “guards” able to sense a wide range of threats upon the body (such as infections or environmental toxins).  When a mast cell senses a threat, it “activates,” producing and releasing chemical signals (“mediators”) appropriate for assisting the body in managing the threat.  In mast cell activation diseases (such as Mastocytosis …

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